Bodybuilders and others who wish to build muscle make use of Dindolyl Methane (or DIM). Recent studies have revealed that DIM can pose health risks. DIM can cause liver damage if taken in excess. Kidney damage can also be an issue, and could result in kidney failure. The long-term health risks associated with DIM make many bodybuilders and athletes ask the question: should I supplement my diet with supplements with DIM?
To increase the production of testosterone it is common to take diindolylmethane supplement. Testosterone is known to act as an androgen, which means that it can trigger hormonal changes in tissues. DIM has been demonstrated in studies to mimic the effects of testosterone, along with other hormones. Certain manufacturers have added diindolylmethane (DIM) to their products to boost their marketability in male circles because men produce more testosterone than women do. Men will respond to products that mimic testosterone naturally.
In the end, many companies market DIM as a cancer-fighter. It is true that diindolylmethane can decrease the growth of tumors in laboratory animals, however the animals were given the drug, not orally. To get the same effect in humans, diindolylmethane has to be consumed at high doses over a prolonged period of time. The animals that were examined had no signs of cancer for many years. However, they all developed liver diseases after consuming excessive amounts of diindolylmethane. A doctor can give you a better understanding of the way DIM functions within the body.
The only way to establish that DIM is effective in treating breast cancer is to conduct an experiment in which cells from healthy breast cells are exposed to high doses of diindolylmethane over long periods of time. There are pros and cons to using DIM, just like any chemical. Its advantages include the capability to mimic hormones. This means that you can create insulin, which can reduce the proliferation of cancerous cells. Cons include the fact that diindolylmethane produces a damaging chemicals called DMSO. Know more about dim diindolylmethane now.
One of the most common claims made for diindolylmethane as a treatment for various health problems is that it can act as a natural, anti-fungal, anti-bacterial and anti-cancer drug. These claims were rejected by the National Institute of Health after an exhaustive review of supporting data. According to the Institute of Chemical Technology, there was no research conducted to prove this claim. In a thorough examination of the safety characteristics of the firestone the Institute of Chemical Safety concluded that the evidence of pharmaceutical companies about the human benefits of diindolylmethane were not reliable.
In the May 2021 edition of the Journal of Toxicology and Environmental Health, van der Goes, and colleagues. Van der Goes, et al. have highlighted the potential risks of diindolylmethane use, including allergic reactions to the skin asthma attacks, as well as dizziness, headaches and respiratory issues. They also stated that the recommended daily allowance for this chemical is 0.2 milligrams, which is about one 10th of one teaspoon. It is unclear what the concentration is when this chemical is paired with other substances. Because this substance has not been thoroughly tested, it is not considered to be safe at any level.
The abstract of the view indicates that the use of diindolylmethane (DIEM) in the context of treating cancer is based on the principle of blocking the intracellular inhibition of pyruvate’s pyruvate metabolite via flavenoids, and thereby stopping the accumulation of oxalates within renal tubule cells and adenine granulocytes. However, the metabiplicate drug toxicity studies did not present convincing evidence that the consumption of this chemical causes an overdose. In June 1996, the Food and Drug Administration approved this drug as a prescribed drug. According to the FDA the company that manufactures firestone Tincture is currently completing two major trials in Europe and the United States.
The view abstract also shows that diindolylmethane’s usage in cancer treatment is based on the concept of inhibiting intracellular inhibition through flavenoids that regulate pyruvate metabolism and thus hindering the accumulation of adenine and oxalates within renal tubule cells. Metabiplicate toxicology studies on the drug have not proven that this chemical is able to cause overdose. The Food and Drug Administration approved this substance as a prescribed drug in June 1996. According to the FDA the company that makes firestone tincture is in process of completing two major studies – one in Europe and one in the United States. According to FDA, the FDA states that the manufacturer of the tincture is currently conducting two major studies in Europe and one in the United States.